The Advocate reports the 20-count indictment, unsealed Wednesday, is the result of a more than yearlong investigation involving multiple law enforcement agencies in Acadiana.
Prosecutors say methamphetamine was purchased in large quantities in Texas and then distributed throughout southwest Louisiana, mainly Lafayette and New Iberia, over several months in 2014.
Iberia Sheriff Louis Ackal says the case is further evidence that the drug is now firmly established in south Louisiana.
Twelve of the 14 people charged had been arrested as of Wednesday.
Information from: The Advocate, http://theadvocate.com